BDBM50032666 6-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-vinyl]-nicotinic acid::CHEMBL109117

SMILES: Cc1cc2c(cc1C(=C)c1ccc(cn1)C(O)=O)C(C)(C)CCC2(C)C

InChI Key: InChIKey=ALRYLNXZUBATMZ-UHFFFAOYSA-N

Data: 3 Kd  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50032666   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinoic acid receptor RXR-gamma (Mus musculus)	BDBM50032666 (6-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-nap...) Show SMILES Cc1cc2c(cc1C(=C)c1ccc(cn1)C(O)=O)C(C)(C)CCC2(C)C Show InChI InChI=1S/C23H27NO2/c1-14-11-18-19(23(5,6)10-9-22(18,3)4)12-17(14)15(2)20-8-7-16(13-24-20)21(25)26/h7-8,11-13H,2,9-10H2,1,3-6H3,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	5	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Ability to activate gene expression at Retinoic acid receptor RXR-gamma was evaluated in a cotransfection assay.				J Med Chem 38: 3146-55 (1995) BindingDB Entry DOI: 10.7270/Q2542MMT
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50032666 (6-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-nap...) Show SMILES Cc1cc2c(cc1C(=C)c1ccc(cn1)C(O)=O)C(C)(C)CCC2(C)C Show InChI InChI=1S/C23H27NO2/c1-14-11-18-19(23(5,6)10-9-22(18,3)4)12-17(14)15(2)20-8-7-16(13-24-20)21(25)26/h7-8,11-13H,2,9-10H2,1,3-6H3,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	6	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Ability to activate gene expression at Retinoic acid receptor RXR-alpha was evaluated in a cotransfection assay.				J Med Chem 38: 3146-55 (1995) BindingDB Entry DOI: 10.7270/Q2542MMT
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-beta (Mus musculus)	BDBM50032666 (6-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-nap...) Show SMILES Cc1cc2c(cc1C(=C)c1ccc(cn1)C(O)=O)C(C)(C)CCC2(C)C Show InChI InChI=1S/C23H27NO2/c1-14-11-18-19(23(5,6)10-9-22(18,3)4)12-17(14)15(2)20-8-7-16(13-24-20)21(25)26/h7-8,11-13H,2,9-10H2,1,3-6H3,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	9	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Ability to activate gene expression at Retinoic acid receptor RXR-beta was evaluated in a cotransfection assay.				J Med Chem 38: 3146-55 (1995) BindingDB Entry DOI: 10.7270/Q2542MMT
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50032666 (6-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-nap...) Show SMILES Cc1cc2c(cc1C(=C)c1ccc(cn1)C(O)=O)C(C)(C)CCC2(C)C Show InChI InChI=1S/C23H27NO2/c1-14-11-18-19(23(5,6)10-9-22(18,3)4)12-17(14)15(2)20-8-7-16(13-24-20)21(25)26/h7-8,11-13H,2,9-10H2,1,3-6H3,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Ability to bind directly to Retinoic acid receptor RXR-alpha was evaluated in a competitive binding assay.				J Med Chem 38: 3146-55 (1995) BindingDB Entry DOI: 10.7270/Q2542MMT
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-gamma (Mus musculus)	BDBM50032666 (6-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-nap...) Show SMILES Cc1cc2c(cc1C(=C)c1ccc(cn1)C(O)=O)C(C)(C)CCC2(C)C Show InChI InChI=1S/C23H27NO2/c1-14-11-18-19(23(5,6)10-9-22(18,3)4)12-17(14)15(2)20-8-7-16(13-24-20)21(25)26/h7-8,11-13H,2,9-10H2,1,3-6H3,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Binding affinity to Retinoic acid receptor RXR-gamma was evaluated in a competitive binding assay.				J Med Chem 38: 3146-55 (1995) BindingDB Entry DOI: 10.7270/Q2542MMT
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-beta (Mus musculus)	BDBM50032666 (6-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-nap...) Show SMILES Cc1cc2c(cc1C(=C)c1ccc(cn1)C(O)=O)C(C)(C)CCC2(C)C Show InChI InChI=1S/C23H27NO2/c1-14-11-18-19(23(5,6)10-9-22(18,3)4)12-17(14)15(2)20-8-7-16(13-24-20)21(25)26/h7-8,11-13H,2,9-10H2,1,3-6H3,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Binding affinity to Retinoic acid receptor RXR-beta was determined in a competitive binding assay.				J Med Chem 38: 3146-55 (1995) BindingDB Entry DOI: 10.7270/Q2542MMT
					More data for this Ligand-Target Pair