null

SMILES: Cn1cnc(NC(=O)c2cccc(c2)-n2cc(NC(=O)Nc3ccccc3Cl)cn2)n1

InChI Key: InChIKey=WWNTZNJRZKYEDT-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50032751   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM50032751 (CHEMBL3355173) Show SMILES Cn1cnc(NC(=O)c2cccc(c2)-n2cc(NC(=O)Nc3ccccc3Cl)cn2)n1 Show InChI InChI=1S/C20H17ClN8O2/c1-28-12-22-19(27-28)26-18(30)13-5-4-6-15(9-13)29-11-14(10-23-29)24-20(31)25-17-8-3-2-7-16(17)21/h2-12H,1H3,(H2,24,25,31)(H,26,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
Translational Research Institute Curated by ChEMBL					Assay Description Inhibition of JNK1 (unknown origin) after 1 hr by homogeneous time-resolved fluorescence assay				J Med Chem 57: 10013-30 (2014) Article DOI: 10.1021/jm501256y BindingDB Entry DOI: 10.7270/Q25140TS
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50032751 (CHEMBL3355173) Show SMILES Cn1cnc(NC(=O)c2cccc(c2)-n2cc(NC(=O)Nc3ccccc3Cl)cn2)n1 Show InChI InChI=1S/C20H17ClN8O2/c1-28-12-22-19(27-28)26-18(30)13-5-4-6-15(9-13)29-11-14(10-23-29)24-20(31)25-17-8-3-2-7-16(17)21/h2-12H,1H3,(H2,24,25,31)(H,26,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	594	n/a	n/a	n/a	n/a	n/a	n/a
Translational Research Institute Curated by ChEMBL					Assay Description Inhibition of JNK3alpha1 (unknown origin) after 1 hr by homogeneous time-resolved fluorescence assay				J Med Chem 57: 10013-30 (2014) Article DOI: 10.1021/jm501256y BindingDB Entry DOI: 10.7270/Q25140TS
					More data for this Ligand-Target Pair