BDBM50032756 CHEMBL3355167

SMILES: Cc1ncc(NC(=O)c2cccc(c2)-n2cc(NC(=O)Nc3ccccc3Cl)cn2)cn1

InChI Key: InChIKey=SRJUPLSEYKRYTF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50032756   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM50032756 (CHEMBL3355167) Show SMILES Cc1ncc(NC(=O)c2cccc(c2)-n2cc(NC(=O)Nc3ccccc3Cl)cn2)cn1 Show InChI InChI=1S/C22H18ClN7O2/c1-14-24-10-16(11-25-14)27-21(31)15-5-4-6-18(9-15)30-13-17(12-26-30)28-22(32)29-20-8-3-2-7-19(20)23/h2-13H,1H3,(H,27,31)(H2,28,29,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	537	n/a	n/a	n/a	n/a	n/a	n/a
Translational Research Institute Curated by ChEMBL					Assay Description Inhibition of JNK1 (unknown origin) after 1 hr by homogeneous time-resolved fluorescence assay				J Med Chem 57: 10013-30 (2014) Article DOI: 10.1021/jm501256y BindingDB Entry DOI: 10.7270/Q25140TS
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50032756 (CHEMBL3355167) Show SMILES Cc1ncc(NC(=O)c2cccc(c2)-n2cc(NC(=O)Nc3ccccc3Cl)cn2)cn1 Show InChI InChI=1S/C22H18ClN7O2/c1-14-24-10-16(11-25-14)27-21(31)15-5-4-6-18(9-15)30-13-17(12-26-30)28-22(32)29-20-8-3-2-7-19(20)23/h2-13H,1H3,(H,27,31)(H2,28,29,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
Translational Research Institute Curated by ChEMBL					Assay Description Inhibition of JNK3alpha1 (unknown origin) after 1 hr by homogeneous time-resolved fluorescence assay				J Med Chem 57: 10013-30 (2014) Article DOI: 10.1021/jm501256y BindingDB Entry DOI: 10.7270/Q25140TS
					More data for this Ligand-Target Pair