BDBM50033036 CHEMBL419574::[2-(1H-Imidazol-4-yl)-ethyl]-(5-nitro-pyridin-2-yl)-amine

SMILES: [O-][N+](=O)c1ccc(NCCc2cnc[nH]2)nc1

InChI Key: InChIKey=SHUOJQMXDFQLNL-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50033036   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50033036 (CHEMBL419574 | [2-(1H-Imidazol-4-yl)-ethyl]-(5-nit...) Show SMILES [O-][N+](=O)c1ccc(NCCc2cnc[nH]2)nc1 Show InChI InChI=1S/C10H11N5O2/c16-15(17)9-1-2-10(13-6-9)12-4-3-8-5-11-7-14-8/h1-2,5-7H,3-4H2,(H,11,14)(H,12,13)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Rat Histamine H3 receptor antagonism determined by [K+] - evoked depolarization-induced release of [3H]-histamine from rat cerebral cortex synaptosom...				J Med Chem 39: 3806-13 (1996) Article DOI: 10.1021/jm960138l BindingDB Entry DOI: 10.7270/Q20P0Z3F
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50033036 (CHEMBL419574 | [2-(1H-Imidazol-4-yl)-ethyl]-(5-nit...) Show SMILES [O-][N+](=O)c1ccc(NCCc2cnc[nH]2)nc1 Show InChI InChI=1S/C10H11N5O2/c16-15(17)9-1-2-10(13-6-9)12-4-3-8-5-11-7-14-8/h1-2,5-7H,3-4H2,(H,11,14)(H,12,13)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description In vitro antagonism of the histamine H3-receptor in the rat cerebral cortex.				J Med Chem 38: 3342-50 (1995) BindingDB Entry DOI: 10.7270/Q2CN72X5
					More data for this Ligand-Target Pair