BDBM50033106 CHEMBL3357066

SMILES: CN1CCN(CC1)c1cccc(c1)-c1ncc2CCN(CCCN3CCOCC3)c2n1

InChI Key: InChIKey=SERXWDBQWPRELR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50033106   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 9 (Homo sapiens (Human))	BDBM50033106 (CHEMBL3357066) Show SMILES CN1CCN(CC1)c1cccc(c1)-c1ncc2CCN(CCCN3CCOCC3)c2n1 Show InChI InChI=1S/C24H34N6O/c1-27-10-12-29(13-11-27)22-5-2-4-20(18-22)23-25-19-21-6-9-30(24(21)26-23)8-3-7-28-14-16-31-17-15-28/h2,4-5,18-19H,3,6-17H2,1H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
Sumitomo Dainippon Pharma Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human TLR9 transfected in HEK293 cells after 6 hrs by NF-kappaB luciferase reporter assay				ACS Med Chem Lett 5: 1235-9 (2014) Article DOI: 10.1021/ml5003184 BindingDB Entry DOI: 10.7270/Q2M32XBN
					More data for this Ligand-Target Pair