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SMILES: Cc1nc2cnccc2n1-c1ccc(cc1)C1=Nc2cc(Cl)c(Cl)cc2C(=O)NC1

InChI Key: InChIKey=HTGJLPLFDGFCBG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50033217   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-activating factor receptor


(Cavia porcellus)		BDBM50033217
PNG
(7,8-Dichloro-2-[4-(2-methyl-imidazo[4,5-c]pyridin-...)
Show SMILES Cc1nc2cnccc2n1-c1ccc(cc1)C1=Nc2cc(Cl)c(Cl)cc2C(=O)NC1 |t:19|
Show InChI InChI=1S/C22H15Cl2N5O/c1-12-27-20-10-25-7-6-21(20)29(12)14-4-2-13(3-5-14)19-11-26-22(30)15-8-16(23)17(24)9-18(15)28-19/h2-10H,11H2,1H3,(H,26,30)
MMDB

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n/an/a 4n/an/an/an/an/an/a



Pfizer Central Research

Curated by ChEMBL


Assay Description
Antagonistic activity was tested against Platelet-Activating Factor-induced aggregation of rabbit washed platelets.

J Med Chem 38: 3514-23 (1995)


BindingDB Entry DOI: 10.7270/Q2PK0GSS
More data for this
Ligand-Target Pair