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SMILES: CN1c2ncc(Br)cc2N=C(CC1=O)c1ccc(cc1)-n1c(C)nc2cnccc12

InChI Key: InChIKey=INTHZPIXJSURQD-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50033245   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-activating factor receptor


(Cavia porcellus)		BDBM50033245
PNG
(8-Bromo-5-methyl-2-[4-(2-methyl-imidazo[4,5-c]pyri...)
Show SMILES CN1c2ncc(Br)cc2N=C(CC1=O)c1ccc(cc1)-n1c(C)nc2cnccc12 |c:10|
Show InChI InChI=1S/C22H17BrN6O/c1-13-26-19-12-24-8-7-20(19)29(13)16-5-3-14(4-6-16)17-10-21(30)28(2)22-18(27-17)9-15(23)11-25-22/h3-9,11-12H,10H2,1-2H3
MMDB

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Similars
PubMed
n/an/a 1.40n/an/an/an/an/an/a



Pfizer Central Research

Curated by ChEMBL


Assay Description
In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets

J Med Chem 38: 3524-35 (1995)


BindingDB Entry DOI: 10.7270/Q2JS9R2X
More data for this
Ligand-Target Pair