BindingDB logo
myBDB logout

null

SMILES: CN1c2c(N=C(CC1=O)c1ccc(cc1)-n1c(C)nc3cnccc13)c(nn2C)-c1cccnc1

InChI Key: InChIKey=NGIATVCYOFEYDQ-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50033251   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-activating factor receptor


(Cavia porcellus)		BDBM50033251
PNG
(1,8-Dimethyl-5-[4-(2-methyl-imidazo[4,5-c]pyridin-...)
Show SMILES CN1c2c(N=C(CC1=O)c1ccc(cc1)-n1c(C)nc3cnccc13)c(nn2C)-c1cccnc1 |c:4|
Show InChI InChI=1S/C26H22N8O/c1-16-29-21-15-28-12-10-22(21)34(16)19-8-6-17(7-9-19)20-13-23(35)32(2)26-25(30-20)24(31-33(26)3)18-5-4-11-27-14-18/h4-12,14-15H,13H2,1-3H3
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
PubMed
n/an/a 2.40n/an/an/an/an/an/a



Pfizer Central Research

Curated by ChEMBL


Assay Description
In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets

J Med Chem 38: 3524-35 (1995)


BindingDB Entry DOI: 10.7270/Q2JS9R2X
More data for this
Ligand-Target Pair