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SMILES: CN1c2c(N=C(CC1=O)c1ccc(cc1)-n1c(C)nc3cnccc13)c(nn2C)-c1cccs1

InChI Key: InChIKey=NFBWKDIKGMERSD-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50033255   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-activating factor receptor


(Cavia porcellus)		BDBM50033255
PNG
(1,8-Dimethyl-5-[4-(2-methyl-imidazo[4,5-c]pyridin-...)
Show SMILES CN1c2c(N=C(CC1=O)c1ccc(cc1)-n1c(C)nc3cnccc13)c(nn2C)-c1cccs1 |c:4|
Show InChI InChI=1S/C25H21N7OS/c1-15-27-19-14-26-11-10-20(19)32(15)17-8-6-16(7-9-17)18-13-22(33)30(2)25-24(28-18)23(29-31(25)3)21-5-4-12-34-21/h4-12,14H,13H2,1-3H3
MMDB

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PubMed
n/an/a 1.5n/an/an/an/an/an/a



Pfizer Central Research

Curated by ChEMBL


Assay Description
In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets

J Med Chem 38: 3524-35 (1995)


BindingDB Entry DOI: 10.7270/Q2JS9R2X
More data for this
Ligand-Target Pair