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SMILES: CN1c2c(N=C(CC1=O)c1ccc(cc1)-n1c(C)nc3cnccc13)c(nn2C)-c1ccccn1

InChI Key: InChIKey=LENCRYIEJPVWQL-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50033261   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-activating factor receptor


(Cavia porcellus)		BDBM50033261
PNG
(1,8-Dimethyl-5-[4-(2-methyl-imidazo[4,5-c]pyridin-...)
Show SMILES CN1c2c(N=C(CC1=O)c1ccc(cc1)-n1c(C)nc3cnccc13)c(nn2C)-c1ccccn1 |c:4|
Show InChI InChI=1S/C26H22N8O/c1-16-29-21-15-27-13-11-22(21)34(16)18-9-7-17(8-10-18)20-14-23(35)32(2)26-25(30-20)24(31-33(26)3)19-6-4-5-12-28-19/h4-13,15H,14H2,1-3H3
MMDB

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PubMed
n/an/a 14n/an/an/an/an/an/a



Pfizer Central Research

Curated by ChEMBL


Assay Description
In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets

J Med Chem 38: 3524-35 (1995)


BindingDB Entry DOI: 10.7270/Q2JS9R2X
More data for this
Ligand-Target Pair