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SMILES: Cc1nc2cnccc2n1-c1ccc(cc1)C1=Nc2ncc(Br)cc2NC(=O)C1

InChI Key: InChIKey=LDXCAOJWIUQHLY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50033267   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-activating factor receptor


(Cavia porcellus)		BDBM50033267
PNG
(8-Bromo-4-[4-(2-methyl-imidazo[4,5-c]pyridin-1-yl)...)
Show SMILES Cc1nc2cnccc2n1-c1ccc(cc1)C1=Nc2ncc(Br)cc2NC(=O)C1 |t:19|
Show InChI InChI=1S/C21H15BrN6O/c1-12-25-18-11-23-7-6-19(18)28(12)15-4-2-13(3-5-15)16-9-20(29)26-17-8-14(22)10-24-21(17)27-16/h2-8,10-11H,9H2,1H3,(H,26,29)
MMDB

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Similars
PubMed
n/an/a 5.60n/an/an/an/an/an/a



Pfizer Central Research

Curated by ChEMBL


Assay Description
In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets

J Med Chem 38: 3524-35 (1995)


BindingDB Entry DOI: 10.7270/Q2JS9R2X
More data for this
Ligand-Target Pair