BDBM50033315 (6-Chloro-2-pyridin-3-yl-quinazolin-4-yl)-furan-2-ylmethyl-amine; dihydrochloride::CHEMBL553819

SMILES: Clc1ccc2nc(nc(NCc3ccco3)c2c1)-c1cccnc1

InChI Key: InChIKey=ARDQFKLCHFGOSJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50033315   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50033315 ((6-Chloro-2-pyridin-3-yl-quinazolin-4-yl)-furan-2-...) Show SMILES Clc1ccc2nc(nc(NCc3ccco3)c2c1)-c1cccnc1 Show InChI InChI=1S/C18H13ClN4O/c19-13-5-6-16-15(9-13)18(21-11-14-4-2-8-24-14)23-17(22-16)12-3-1-7-20-10-12/h1-10H,11H2,(H,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Biofor Inc. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 5 from human platelets				J Med Chem 38: 3547-57 (1995) BindingDB Entry DOI: 10.7270/Q2F190CB
					More data for this Ligand-Target Pair