BDBM50033813 1-Benzyl-3-(3,5-bis-trifluoromethyl-benzyl)-5-(1H-indol-3-ylmethyl)-imidazolidine-2,4-dione::CHEMBL427295

SMILES: Oc1c(Cc2c[nH]c3ccccc23)n(Cc2ccccc2)c(=O)n1Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=CBAOJWSPVQYBKA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50033813   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neurokinin 1 receptor (Homo sapiens (Human))	BDBM50033813 (1-Benzyl-3-(3,5-bis-trifluoromethyl-benzyl)-5-(1H-...) Show SMILES Oc1c(Cc2c[nH]c3ccccc23)n(Cc2ccccc2)c(=O)n1Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C28H21F6N3O2/c29-27(30,31)20-10-18(11-21(13-20)28(32,33)34)16-37-25(38)24(12-19-14-35-23-9-5-4-8-22(19)23)36(26(37)39)15-17-6-2-1-3-7-17/h1-11,13-14,35,38H,12,15-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp& Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity at human Tachykinin receptor 1 expressed in CHO cells by [125 I]Trp8-substance P displacement.				J Med Chem 38: 923-33 (1995) BindingDB Entry DOI: 10.7270/Q25D8SG4
					More data for this Ligand-Target Pair