BDBM50033824 3-(3,5-Bis-trifluoromethyl-benzyl)-5-(1H-indol-3-ylmethyl)-imidazolidine-2,4-dione::CHEMBL369580

SMILES: Oc1c(Cc2c[nH]c3ccccc23)[nH]c(=O)n1Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=DORRAMIKPVODSI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50033824   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neurokinin 1 receptor (Homo sapiens (Human))	BDBM50033824 (3-(3,5-Bis-trifluoromethyl-benzyl)-5-(1H-indol-3-y...) Show SMILES Oc1c(Cc2c[nH]c3ccccc23)[nH]c(=O)n1Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C21H15F6N3O2/c22-20(23,24)13-5-11(6-14(8-13)21(25,26)27)10-30-18(31)17(29-19(30)32)7-12-9-28-16-4-2-1-3-15(12)16/h1-6,8-9,28,31H,7,10H2,(H,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	317	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp& Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity at human Tachykinin receptor 1 expressed in CHO cells by [125 I]Trp8-substance P displacement.				J Med Chem 38: 923-33 (1995) BindingDB Entry DOI: 10.7270/Q25D8SG4
					More data for this Ligand-Target Pair