BDBM50033832 1-[3-(7-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-4-(3-trifluoromethyl-phenyl)-piperazine::CHEMBL367723

SMILES: COc1ccc2CCCC(CCCN3CCN(CC3)c3cccc(c3)C(F)(F)F)c2c1

InChI Key: InChIKey=XGJBTUNWSSZAJD-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50033832   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50033832 (1-[3-(7-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl...) Show SMILES COc1ccc2CCCC(CCCN3CCN(CC3)c3cccc(c3)C(F)(F)F)c2c1 Show InChI InChI=1S/C25H31F3N2O/c1-31-23-11-10-20-6-2-5-19(24(20)18-23)7-4-12-29-13-15-30(16-14-29)22-9-3-8-21(17-22)25(26,27)28/h3,8-11,17-19H,2,4-7,12-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.33E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università di Bari Curated by ChEMBL					Assay Description In vitro binding affinity measured on dopamine receptor D2 using [3H]-spiroperidol as radioligand.				J Med Chem 38: 942-9 (1995) BindingDB Entry DOI: 10.7270/Q2SQ8ZD0
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50033832 (1-[3-(7-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl...) Show SMILES COc1ccc2CCCC(CCCN3CCN(CC3)c3cccc(c3)C(F)(F)F)c2c1 Show InChI InChI=1S/C25H31F3N2O/c1-31-23-11-10-20-6-2-5-19(24(20)18-23)7-4-12-29-13-15-30(16-14-29)22-9-3-8-21(17-22)25(26,27)28/h3,8-11,17-19H,2,4-7,12-16H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	87.5	n/a	n/a	n/a	n/a	n/a	n/a
Università di Bari Curated by ChEMBL					Assay Description In vitro binding affinity measured on sigma opioid receptor using [3H]-DTG as radioligand				J Med Chem 38: 942-9 (1995) BindingDB Entry DOI: 10.7270/Q2SQ8ZD0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50033832 (1-[3-(7-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl...) Show SMILES COc1ccc2CCCC(CCCN3CCN(CC3)c3cccc(c3)C(F)(F)F)c2c1 Show InChI InChI=1S/C25H31F3N2O/c1-31-23-11-10-20-6-2-5-19(24(20)18-23)7-4-12-29-13-15-30(16-14-29)22-9-3-8-21(17-22)25(26,27)28/h3,8-11,17-19H,2,4-7,12-16H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	88.4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Bari Curated by ChEMBL					Assay Description In vitro binding affinity measured on serotonin 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.				J Med Chem 38: 942-9 (1995) BindingDB Entry DOI: 10.7270/Q2SQ8ZD0
					More data for this Ligand-Target Pair