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SMILES: CN(CC(=O)N(Cc1ccccc1)c1ccc(C(O)=O)c(O)c1)S(=O)(=O)c1c(F)c(F)c(F)c(F)c1F

InChI Key: InChIKey=NQKGDGRWBLCYDF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50033893   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Signal transducer and activator of transcription 5B


(Homo sapiens (Human))		BDBM50033893
PNG
(CHEMBL3358605)
Show SMILES CN(CC(=O)N(Cc1ccccc1)c1ccc(C(O)=O)c(O)c1)S(=O)(=O)c1c(F)c(F)c(F)c(F)c1F
Show InChI InChI=1S/C23H17F5N2O6S/c1-29(37(35,36)22-20(27)18(25)17(24)19(26)21(22)28)11-16(32)30(10-12-5-3-2-4-6-12)13-7-8-14(23(33)34)15(31)9-13/h2-9,31H,10-11H2,1H3,(H,33,34)
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Similars
Article
PubMed
>6.00E+4n/an/an/an/an/an/an/an/a



University of Toronto Mississauga

Curated by ChEMBL


Assay Description
Inhibition of STAT5B SH2 domain (unknown origin)-5-FAM-GpYLVLDKW interaction compound treated for 15 mins by fluorescent polarization assay

ACS Med Chem Lett 5: 1202-1206 (2014)


Article DOI: 10.1021/ml500165r
BindingDB Entry DOI: 10.7270/Q25X2BJJ
More data for this
Ligand-Target Pair