BDBM50033942 5-Ethyl-1-[4-(3-trifluoromethyl-phenyl)-thiazol-2-yl]-1H-pyrazole-4-carboxylic acid (3-hydroxy-propyl)-amide::CHEMBL10101

SMILES: CCc1c(cnn1-c1nc(cs1)-c1cccc(c1)C(F)(F)F)C(=O)NCCCO

InChI Key: InChIKey=MKKMTLJJZXKVQU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50033942   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha-L/beta-2 (Homo sapiens (Human))	BDBM50033942 (5-Ethyl-1-[4-(3-trifluoromethyl-phenyl)-thiazol-2-...) Show SMILES CCc1c(cnn1-c1nc(cs1)-c1cccc(c1)C(F)(F)F)C(=O)NCCCO Show InChI InChI=1S/C19H19F3N4O2S/c1-2-16-14(17(28)23-7-4-8-27)10-24-26(16)18-25-15(11-29-18)12-5-3-6-13(9-12)19(20,21)22/h3,5-6,9-11,27H,2,4,7-8H2,1H3,(H,23,28)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of HL-60 cell adhesion to purified ICAM-1 by LFA-1				J Med Chem 38: 1057-9 (1995) BindingDB Entry DOI: 10.7270/Q2DJ5DPP
					More data for this Ligand-Target Pair