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SMILES: CCCCCCCN(CCCCCSc1nc(c([nH]1)-c1ccc(cc1)N(C)C)-c1ccc(cc1)N(C)C)C(=O)Nc1ccc(F)cc1F

InChI Key: InChIKey=WXDAYDIAZMOMQC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50033952   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sterol O-acyltransferase 1


(Rattus norvegicus)		BDBM50033952
PNG
(1-{5-[4,5-Bis-(4-dimethylamino-phenyl)-1H-imidazol...)
Show SMILES CCCCCCCN(CCCCCSc1nc(c([nH]1)-c1ccc(cc1)N(C)C)-c1ccc(cc1)N(C)C)C(=O)Nc1ccc(F)cc1F
Show InChI InChI=1S/C38H50F2N6OS/c1-6-7-8-9-11-24-46(38(47)41-34-23-18-30(39)27-33(34)40)25-12-10-13-26-48-37-42-35(28-14-19-31(20-15-28)44(2)3)36(43-37)29-16-21-32(22-17-29)45(4)5/h14-23,27H,6-13,24-26H2,1-5H3,(H,41,47)(H,42,43)
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PubMed
n/an/a 50n/an/an/an/an/an/a



DuPont Merck Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.

J Med Chem 38: 1067-83 (1995)


BindingDB Entry DOI: 10.7270/Q28S4P0T
More data for this
Ligand-Target Pair