BDBM50033967 1-(2-Butoxy-ethyl)-3-(2,4-difluoro-phenyl)-1-[5-(4,5-diphenyl-1H-imidazol-2-ylsulfanyl)-pentyl]-urea::CHEMBL268478

SMILES: CCCCOCCN(CCCCCSc1nc(c([nH]1)-c1ccccc1)-c1ccccc1)C(=O)Nc1ccc(F)cc1F

InChI Key: InChIKey=BJILKFRCDKDPMR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50033967   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sterol O-acyltransferase, Soat (Rattus norvegicus)	BDBM50033967 (1-(2-Butoxy-ethyl)-3-(2,4-difluoro-phenyl)-1-[5-(4...) Show SMILES CCCCOCCN(CCCCCSc1nc(c([nH]1)-c1ccccc1)-c1ccccc1)C(=O)Nc1ccc(F)cc1F Show InChI InChI=1S/C33H38F2N4O2S/c1-2-3-21-41-22-20-39(33(40)36-29-18-17-27(34)24-28(29)35)19-11-6-12-23-42-32-37-30(25-13-7-4-8-14-25)31(38-32)26-15-9-5-10-16-26/h4-5,7-10,13-18,24H,2-3,6,11-12,19-23H2,1H3,(H,36,40)(H,37,38)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Merck Research Laboratories Curated by ChEMBL					Assay Description Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.				J Med Chem 38: 1067-83 (1995) BindingDB Entry DOI: 10.7270/Q28S4P0T
					More data for this Ligand-Target Pair