BDBM50034031 6-Fluoro-3-{1-[3-(5-methoxy-1H-indol-6-yloxy)-propyl]-piperidin-4-yl}-benzo[d]isoxazole::CHEMBL14148

SMILES: COc1cc2cc[nH]c2cc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12

InChI Key: InChIKey=VEVRYAZMLSNPBA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50034031   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50034031 (6-Fluoro-3-{1-[3-(5-methoxy-1H-indol-6-yloxy)-prop...) Show SMILES COc1cc2cc[nH]c2cc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12 Show InChI InChI=1S/C24H26FN3O3/c1-29-22-13-17-5-8-26-20(17)15-23(22)30-12-2-9-28-10-6-16(7-11-28)24-19-4-3-18(25)14-21(19)31-27-24/h3-5,8,13-16,26H,2,6-7,9-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	118	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals Inc Curated by ChEMBL					Assay Description Affinity for dopamine receptor D2 binding sites by its ability to displace [3H]spiperone from rat striatum.				J Med Chem 38: 1119-31 (1995) BindingDB Entry DOI: 10.7270/Q2S75H08
					More data for this Ligand-Target Pair