BDBM50034034 1-{4-[4-(4-Benzo[d]isoxazol-3-yl-piperidin-1-yl)-butoxy]-3-methoxy-phenyl}-ethanone::CHEMBL274223

SMILES: COc1cc(ccc1OCCCCN1CCC(CC1)c1noc2ccccc12)C(C)=O

InChI Key: InChIKey=ZDCLHBFINMVMFC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50034034   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50034034 (1-{4-[4-(4-Benzo[d]isoxazol-3-yl-piperidin-1-yl)-b...) Show SMILES COc1cc(ccc1OCCCCN1CCC(CC1)c1noc2ccccc12)C(C)=O Show InChI InChI=1S/C25H30N2O4/c1-18(28)20-9-10-23(24(17-20)29-2)30-16-6-5-13-27-14-11-19(12-15-27)25-21-7-3-4-8-22(21)31-26-25/h3-4,7-10,17,19H,5-6,11-16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals Inc Curated by ChEMBL					Assay Description Affinity for dopamine receptor D2 binding sites by its ability to displace [3H]spiperone from rat striatum.				J Med Chem 38: 1119-31 (1995) BindingDB Entry DOI: 10.7270/Q2S75H08
					More data for this Ligand-Target Pair