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BDBM50034035 1-(2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2,3-dihydro-benzo[1,4]dioxin-6-yl)-ethanone::CHEMBL14043

SMILES: CC(=O)c1ccc2OC(CCN3CCC(CC3)c3noc4cc(F)ccc34)COc2c1

InChI Key: InChIKey=RDYSIFFUFHBZMZ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50034035   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50034035
PNG
(1-(2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperi...)
Show SMILES CC(=O)c1ccc2OC(CCN3CCC(CC3)c3noc4cc(F)ccc34)COc2c1
Show InChI InChI=1S/C24H25FN2O4/c1-15(28)17-2-5-21-23(12-17)29-14-19(30-21)8-11-27-9-6-16(7-10-27)24-20-4-3-18(25)13-22(20)31-26-24/h2-5,12-13,16,19H,6-11,14H2,1H3
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PC cid
PC sid
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Similars
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Hoechst-Roussel Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Affinity for dopamine receptor D2 binding sites by its ability to displace [3H]spiperone from rat striatum.

J Med Chem 38: 1119-31 (1995)


BindingDB Entry DOI: 10.7270/Q2S75H08
More data for this
Ligand-Target Pair