BDBM50034057 1-{4-[2-(4-Benzo[d]isoxazol-3-yl-piperidin-1-yl)-ethoxy]-3-methoxy-phenyl}-ethanone::CHEMBL274462

SMILES: COc1cc(ccc1OCCN1CCC(CC1)c1noc2ccccc12)C(C)=O

InChI Key: InChIKey=WNCLNNYXHNIVAT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50034057   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50034057 (1-{4-[2-(4-Benzo[d]isoxazol-3-yl-piperidin-1-yl)-e...) Show SMILES COc1cc(ccc1OCCN1CCC(CC1)c1noc2ccccc12)C(C)=O Show InChI InChI=1S/C23H26N2O4/c1-16(26)18-7-8-21(22(15-18)27-2)28-14-13-25-11-9-17(10-12-25)23-19-5-3-4-6-20(19)29-24-23/h3-8,15,17H,9-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	969	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals Inc Curated by ChEMBL					Assay Description Affinity for dopamine receptor D2 binding sites by its ability to displace [3H]spiperone from rat striatum.				J Med Chem 38: 1119-31 (1995) BindingDB Entry DOI: 10.7270/Q2S75H08
					More data for this Ligand-Target Pair