BDBM50034060 1-(3-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-phenyl)-ethanone::CHEMBL14158

SMILES: CC(=O)c1cccc(OCCCN2CCC(CC2)c2noc3cc(F)ccc23)c1

InChI Key: InChIKey=LZBWQSMPSLARFG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50034060   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50034060 (1-(3-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperi...) Show SMILES CC(=O)c1cccc(OCCCN2CCC(CC2)c2noc3cc(F)ccc23)c1 Show InChI InChI=1S/C23H25FN2O3/c1-16(27)18-4-2-5-20(14-18)28-13-3-10-26-11-8-17(9-12-26)23-21-7-6-19(24)15-22(21)29-25-23/h2,4-7,14-15,17H,3,8-13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	454	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals Inc Curated by ChEMBL					Assay Description Affinity for dopamine receptor D2 binding sites by its ability to displace [3H]spiperone from rat striatum.				J Med Chem 38: 1119-31 (1995) BindingDB Entry DOI: 10.7270/Q2S75H08
					More data for this Ligand-Target Pair