BDBM50034070 4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-3-methoxy-N,N-dimethyl-benzamide::CHEMBL14415

SMILES: COc1cc(ccc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12)C(=O)N(C)C

InChI Key: InChIKey=LCIPVHBFQNHEJP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50034070   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50034070 (4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...) Show SMILES COc1cc(ccc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12)C(=O)N(C)C Show InChI InChI=1S/C25H30FN3O4/c1-28(2)25(30)18-5-8-21(23(15-18)31-3)32-14-4-11-29-12-9-17(10-13-29)24-20-7-6-19(26)16-22(20)33-27-24/h5-8,15-17H,4,9-14H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	127	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals Inc Curated by ChEMBL					Assay Description Affinity for dopamine receptor D2 binding sites by its ability to displace [3H]spiperone from rat striatum.				J Med Chem 38: 1119-31 (1995) BindingDB Entry DOI: 10.7270/Q2S75H08
					More data for this Ligand-Target Pair