BDBM50034072 1-(4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-3,5-dimethoxy-phenyl)-ethanone::CHEMBL14395

SMILES: COc1cc(cc(OC)c1OCCCN1CCC(CC1)c1noc2cc(F)ccc12)C(C)=O

InChI Key: InChIKey=GWTRXOMITGLYGF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50034072   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50034072 (1-(4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperi...) Show SMILES COc1cc(cc(OC)c1OCCCN1CCC(CC1)c1noc2cc(F)ccc12)C(C)=O Show InChI InChI=1S/C25H29FN2O5/c1-16(29)18-13-22(30-2)25(23(14-18)31-3)32-12-4-9-28-10-7-17(8-11-28)24-20-6-5-19(26)15-21(20)33-27-24/h5-6,13-15,17H,4,7-12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals Inc Curated by ChEMBL					Assay Description Affinity for dopamine receptor D2 binding sites by its ability to displace [3H]spiperone from rat striatum.				J Med Chem 38: 1119-31 (1995) BindingDB Entry DOI: 10.7270/Q2S75H08
					More data for this Ligand-Target Pair