BDBM50034283 CHEMBL26447::N-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-nicotinamide

SMILES: COc1ccccc1N1CCN(CCNC(=O)c2cccnc2)CC1

InChI Key: InChIKey=RPFDZEAPDWUCAQ-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50034283   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50034283 (CHEMBL26447 | N-{2-[4-(2-Methoxy-phenyl)-piperazin...) Show SMILES COc1ccccc1N1CCN(CCNC(=O)c2cccnc2)CC1 Show InChI InChI=1S/C19H24N4O2/c1-25-18-7-3-2-6-17(18)23-13-11-22(12-14-23)10-9-21-19(24)16-5-4-8-20-15-16/h2-8,15H,9-14H2,1H3,(H,21,24)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Pharma Curated by ChEMBL					Assay Description Binding affinity was evaluated by determining in vitro displacement of [3H]-8-OH-DPAT from the central 5-hydroxytryptamine 1A receptor recognition si...				J Med Chem 40: 300-12 (1997) Article DOI: 10.1021/jm960496o BindingDB Entry DOI: 10.7270/Q27W6B96
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50034283 (CHEMBL26447 | N-{2-[4-(2-Methoxy-phenyl)-piperazin...) Show SMILES COc1ccccc1N1CCN(CCNC(=O)c2cccnc2)CC1 Show InChI InChI=1S/C19H24N4O2/c1-25-18-7-3-2-6-17(18)23-13-11-22(12-14-23)10-9-21-19(24)16-5-4-8-20-15-16/h2-8,15H,9-14H2,1H3,(H,21,24)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	362	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
FAES, S.A. Curated by ChEMBL					Assay Description In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.				J Med Chem 38: 1273-7 (1995) BindingDB Entry DOI: 10.7270/Q2H9947K
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50034283 (CHEMBL26447 | N-{2-[4-(2-Methoxy-phenyl)-piperazin...) Show SMILES COc1ccccc1N1CCN(CCNC(=O)c2cccnc2)CC1 Show InChI InChI=1S/C19H24N4O2/c1-25-18-7-3-2-6-17(18)23-13-11-22(12-14-23)10-9-21-19(24)16-5-4-8-20-15-16/h2-8,15H,9-14H2,1H3,(H,21,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	570	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Pharma Curated by ChEMBL					Assay Description In vitro displacement of [3H]-spiperone from Dopamine receptor D2 binding site in rat striatum.				J Med Chem 40: 300-12 (1997) Article DOI: 10.1021/jm960496o BindingDB Entry DOI: 10.7270/Q27W6B96
					More data for this Ligand-Target Pair