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BDBM50034309 3-Methyl-thiophene-2-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide::CHEMBL22427

SMILES: COc1ccccc1N1CCN(CCCCNC(=O)c2sccc2C)CC1

InChI Key: InChIKey=NYSDVJIUWZYMPH-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50034309   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50034309
PNG
(3-Methyl-thiophene-2-carboxylic acid {4-[4-(2-meth...)
Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2sccc2C)CC1
Show InChI InChI=1S/C21H29N3O2S/c1-17-9-16-27-20(17)21(25)22-10-5-6-11-23-12-14-24(15-13-23)18-7-3-4-8-19(18)26-2/h3-4,7-9,16H,5-6,10-15H2,1-2H3,(H,22,25)
PDB

KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
PubMed
 1.53n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.

J Med Chem 38: 1273-7 (1995)


BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair