BDBM50034426 6-Amino-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL281511

SMILES: Cc1noc(NS(=O)(=O)c2cccc3cc(N)ccc23)c1C

InChI Key: InChIKey=ZUSFHCBGYVFRLE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50034426   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
EDNRA (RAT)	BDBM50034426 (6-Amino-naphthalene-1-sulfonic acid (3,4-dimethyl-...) Show SMILES Cc1noc(NS(=O)(=O)c2cccc3cc(N)ccc23)c1C Show InChI InChI=1S/C15H15N3O3S/c1-9-10(2)17-21-15(9)18-22(19,20)14-5-3-4-11-8-12(16)6-7-13(11)14/h3-8,18H,16H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of [125I]-endothelin-l binding to endothelin A receptor of rat thoracic aorta smooth muscle cells				J Med Chem 38: 659-68 (1995) BindingDB Entry DOI: 10.7270/Q2D799G5
					More data for this Ligand-Target Pair
EDNRA (RAT)	BDBM50034426 (6-Amino-naphthalene-1-sulfonic acid (3,4-dimethyl-...) Show SMILES Cc1noc(NS(=O)(=O)c2cccc3cc(N)ccc23)c1C Show InChI InChI=1S/C15H15N3O3S/c1-9-10(2)17-21-15(9)18-22(19,20)14-5-3-4-11-8-12(16)6-7-13(11)14/h3-8,18H,16H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Antagonism of [125 I]ET-1 binding to the rat endothelin receptor in vascular smooth muscle VSM-A10 cells.				J Med Chem 38: 1344-54 (1995) BindingDB Entry DOI: 10.7270/Q20864BS
					More data for this Ligand-Target Pair