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SMILES: Cc1noc(NS(=O)(=O)c2cccc3c(cccc23)N2CCCC2)c1C

InChI Key: InChIKey=RNGKFYCDICNCCX-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50034428   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Endothelin-1 receptor


(RAT)		BDBM50034428
PNG
(5-Pyrrolidin-1-yl-naphthalene-1-sulfonic acid (3,4...)
Show SMILES Cc1noc(NS(=O)(=O)c2cccc3c(cccc23)N2CCCC2)c1C
Show InChI InChI=1S/C19H21N3O3S/c1-13-14(2)20-25-19(13)21-26(23,24)18-10-6-7-15-16(18)8-5-9-17(15)22-11-3-4-12-22/h5-10,21H,3-4,11-12H2,1-2H3
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n/an/a 30n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Antagonism of [125 I]ET-1 binding to the rat endothelin receptor in vascular smooth muscle VSM-A10 cells.

J Med Chem 38: 1344-54 (1995)


BindingDB Entry DOI: 10.7270/Q20864BS
More data for this
Ligand-Target Pair