BDBM50034457 5-(Isopropyl-methyl-amino)-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL283652

SMILES: CC(C)N(C)c1cccc2c(cccc12)S(=O)(=O)Nc1onc(C)c1C

InChI Key: InChIKey=DXCOFYZOPGIJTO-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50034457   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
EDNRA (RAT)	BDBM50034457 (5-(Isopropyl-methyl-amino)-naphthalene-1-sulfonic ...) Show SMILES CC(C)N(C)c1cccc2c(cccc12)S(=O)(=O)Nc1onc(C)c1C Show InChI InChI=1S/C19H23N3O3S/c1-12(2)22(5)17-10-6-9-16-15(17)8-7-11-18(16)26(23,24)21-19-13(3)14(4)20-25-19/h6-12,21H,1-5H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of [125I]-endothelin-l binding to endothelin A receptor of rat thoracic aorta smooth muscle cells				J Med Chem 38: 659-68 (1995) BindingDB Entry DOI: 10.7270/Q2D799G5
					More data for this Ligand-Target Pair
EDNRA (RAT)	BDBM50034457 (5-(Isopropyl-methyl-amino)-naphthalene-1-sulfonic ...) Show SMILES CC(C)N(C)c1cccc2c(cccc12)S(=O)(=O)Nc1onc(C)c1C Show InChI InChI=1S/C19H23N3O3S/c1-12(2)22(5)17-10-6-9-16-15(17)8-7-11-18(16)26(23,24)21-19-13(3)14(4)20-25-19/h6-12,21H,1-5H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Antagonism of [125 I]ET-1 binding to the rat endothelin receptor in vascular smooth muscle VSM-A10 cells.				J Med Chem 38: 1344-54 (1995) BindingDB Entry DOI: 10.7270/Q20864BS
					More data for this Ligand-Target Pair