BDBM50034462 5-Methoxy-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL28692

SMILES: COc1cccc2c(cccc12)S(=O)(=O)Nc1onc(C)c1C

InChI Key: InChIKey=WNTHOLVCVUVGCW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50034462   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50034462 (5-Methoxy-naphthalene-1-sulfonic acid (3,4-dimethy...) Show SMILES COc1cccc2c(cccc12)S(=O)(=O)Nc1onc(C)c1C Show InChI InChI=1S/C16H16N2O4S/c1-10-11(2)17-22-16(10)18-23(19,20)15-9-5-6-12-13(15)7-4-8-14(12)21-3/h4-9,18H,1-3H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Ability to inhibit [125I]-ET1 binding to vascular smooth muscle (vsm)- A10 cells				J Med Chem 37: 329-31 (1994) BindingDB Entry DOI: 10.7270/Q24M93KB
					More data for this Ligand-Target Pair
EDNRA (RAT)	BDBM50034462 (5-Methoxy-naphthalene-1-sulfonic acid (3,4-dimethy...) Show SMILES COc1cccc2c(cccc12)S(=O)(=O)Nc1onc(C)c1C Show InChI InChI=1S/C16H16N2O4S/c1-10-11(2)17-22-16(10)18-23(19,20)15-9-5-6-12-13(15)7-4-8-14(12)21-3/h4-9,18H,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Antagonism of [125 I]ET-1 binding to the rat endothelin receptor in vascular smooth muscle VSM-A10 cells.				J Med Chem 38: 1344-54 (1995) BindingDB Entry DOI: 10.7270/Q20864BS
					More data for this Ligand-Target Pair