BDBM50034814 CHEMBL3338092

SMILES: Cc1c(Cc2ccc(cc2S(=O)(=O)c2ccccc2)C(F)(F)F)c2c(CCNC2=O)n1CC(O)=O

InChI Key: InChIKey=FJIQYKPENVNXSG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50034814   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM50034814 (CHEMBL3338092) Show SMILES Cc1c(Cc2ccc(cc2S(=O)(=O)c2ccccc2)C(F)(F)F)c2c(CCNC2=O)n1CC(O)=O Show InChI InChI=1S/C24H21F3N2O5S/c1-14-18(22-19(9-10-28-23(22)32)29(14)13-21(30)31)11-15-7-8-16(24(25,26)27)12-20(15)35(33,34)17-5-3-2-4-6-17/h2-8,12H,9-11,13H2,1H3,(H,28,32)(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTh2 (unknown origin) stably expressed in PGD2-stimulated CHO.K1 cells preincubated for 1 hr by radio-labelled [35S]-GTPgamma...				Bioorg Med Chem Lett 24: 5111-7 (2014) Article DOI: 10.1016/j.bmcl.2014.08.026 BindingDB Entry DOI: 10.7270/Q2N01840
					More data for this Ligand-Target Pair