BDBM50034850 (R)-2-[(S)-3-Biphenyl-4-yl-2-(2-carboxy-2-hydroxy-ethylcarbamoyl)-propyl]-hexanoic acid::CHEMBL296760
SMILES: CCCC[C@H](C[C@@H](Cc1ccc(cc1)-c1ccccc1)C(=O)NCC(O)C(O)=O)C(O)=O
InChI Key: InChIKey=MKBUPSIAEKNMBU-JAZPPYFYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neutral Endopeptidase (NEP) (Rattus norvegicus (Rat)) | BDBM50034850 ((R)-2-[(S)-3-Biphenyl-4-yl-2-(2-carboxy-2-hydroxy-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description In vitro inhibition of rat neutral endopeptidase by using GAAP as substrate | J Med Chem 38: 1689-700 (1995) BindingDB Entry DOI: 10.7270/Q2Z89BD0 | |||||||||||
More data for this Ligand-Target Pair |