BDBM50034852 (2R,4S)-2-Benzyl-4-(3-carboxy-propionylamino)-5-phenyl-pentanoic acid::CHEMBL46611

SMILES: OC(=O)CCC(=O)N[C@@H](C[C@@H](Cc1ccccc1)C(O)=O)Cc1ccccc1

InChI Key: InChIKey=JMXUCPBUINCOSV-RTBURBONSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50034852   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neutral Endopeptidase (NEP) (Rattus norvegicus (Rat))	BDBM50034852 ((2R,4S)-2-Benzyl-4-(3-carboxy-propionylamino)-5-ph...) Show SMILES OC(=O)CCC(=O)N[C@@H](C[C@@H](Cc1ccccc1)C(O)=O)Cc1ccccc1 Show InChI InChI=1S/C22H25NO5/c24-20(11-12-21(25)26)23-19(14-17-9-5-2-6-10-17)15-18(22(27)28)13-16-7-3-1-4-8-16/h1-10,18-19H,11-15H2,(H,23,24)(H,25,26)(H,27,28)/t18-,19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description In vitro inhibition of rat neutral endopeptidase by using GAAP as substrate				J Med Chem 38: 1689-700 (1995) BindingDB Entry DOI: 10.7270/Q2Z89BD0
					More data for this Ligand-Target Pair