BDBM50034853 (R)-2-[(S)-3-Biphenyl-4-yl-2-(2-carboxy-ethylcarbamoyl)-propyl]-hexanoic acid::CHEMBL296499

SMILES: CCCC[C@H](C[C@@H](Cc1ccc(cc1)-c1ccccc1)C(=O)NCCC(O)=O)C(O)=O

InChI Key: InChIKey=BLXORZIAQIOBPU-FGZHOGPDSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50034853   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neutral Endopeptidase (NEP) (Rattus norvegicus (Rat))	BDBM50034853 ((R)-2-[(S)-3-Biphenyl-4-yl-2-(2-carboxy-ethylcarba...) Show SMILES CCCC[C@H](C[C@@H](Cc1ccc(cc1)-c1ccccc1)C(=O)NCCC(O)=O)C(O)=O Show InChI InChI=1S/C25H31NO5/c1-2-3-7-21(25(30)31)17-22(24(29)26-15-14-23(27)28)16-18-10-12-20(13-11-18)19-8-5-4-6-9-19/h4-6,8-13,21-22H,2-3,7,14-17H2,1H3,(H,26,29)(H,27,28)(H,30,31)/t21-,22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description In vitro inhibition of rat neutral endopeptidase by using GAAP as substrate				J Med Chem 38: 1689-700 (1995) BindingDB Entry DOI: 10.7270/Q2Z89BD0
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