BDBM50034861 (2S,4S)-5-Biphenyl-4-yl-4-(2-carboxy-ethylcarbamoyl)-2-(3,4-dimethoxy-benzyl)-pentanoic acid::CHEMBL416093

SMILES: COc1ccc(C[C@H](C[C@@H](Cc2ccc(cc2)-c2ccccc2)C(=O)NCCC(O)=O)C(O)=O)cc1OC

InChI Key: InChIKey=GEUHHMCKIKPDTH-JWQCQUIFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50034861   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neprilysin (Rattus norvegicus (Rat))	BDBM50034861 ((2S,4S)-5-Biphenyl-4-yl-4-(2-carboxy-ethylcarbamoy...) Show SMILES COc1ccc(C[C@H](C[C@@H](Cc2ccc(cc2)-c2ccccc2)C(=O)NCCC(O)=O)C(O)=O)cc1OC Show InChI InChI=1S/C30H33NO7/c1-37-26-13-10-21(18-27(26)38-2)17-25(30(35)36)19-24(29(34)31-15-14-28(32)33)16-20-8-11-23(12-9-20)22-6-4-3-5-7-22/h3-13,18,24-25H,14-17,19H2,1-2H3,(H,31,34)(H,32,33)(H,35,36)/t24-,25-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description In vitro inhibition of rat neutral endopeptidase by using GAAP as substrate				J Med Chem 38: 1689-700 (1995) BindingDB Entry DOI: 10.7270/Q2Z89BD0
					More data for this Ligand-Target Pair