BDBM50034862 (2S,4S)-5-Biphenyl-4-yl-4-(2-carboxy-ethylcarbamoyl)-2-p-tolyl-pentanoic acid::CHEMBL301159

SMILES: Cc1ccc(cc1)[C@H](C[C@@H](Cc1ccc(cc1)-c1ccccc1)C(=O)NCCC(O)=O)C(O)=O

InChI Key: InChIKey=ANAUDJHBMPCLLI-RPBOFIJWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50034862   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neutral Endopeptidase (NEP) (Rattus norvegicus (Rat))	BDBM50034862 ((2S,4S)-5-Biphenyl-4-yl-4-(2-carboxy-ethylcarbamoy...) Show SMILES Cc1ccc(cc1)[C@H](C[C@@H](Cc1ccc(cc1)-c1ccccc1)C(=O)NCCC(O)=O)C(O)=O Show InChI InChI=1S/C28H29NO5/c1-19-7-11-23(12-8-19)25(28(33)34)18-24(27(32)29-16-15-26(30)31)17-20-9-13-22(14-10-20)21-5-3-2-4-6-21/h2-14,24-25H,15-18H2,1H3,(H,29,32)(H,30,31)(H,33,34)/t24-,25+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description In vitro inhibition of rat neutral endopeptidase by using GAAP as substrate				J Med Chem 38: 1689-700 (1995) BindingDB Entry DOI: 10.7270/Q2Z89BD0
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