BDBM50034912 (S)-2-((R)-2-Acetylamino-3-phenyl-propionylamino)-5-guanidino-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide::Ac-DPhe-Arg-Trp-NH2::CHEMBL432895
SMILES: CC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
InChI Key: InChIKey=LUCUFURZWPZEOH-KMDXXIMOSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Melanocortin receptor 3 (Homo sapiens (Human)) | BDBM50034912 ((S)-2-((R)-2-Acetylamino-3-phenyl-propionylamino)-...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Michigan Medical Center Curated by ChEMBL | Assay Description Displacement of [125I]NDP-MSH from Melanocortin 3 receptor at 10 uM | J Med Chem 40: 2133-9 (1997) Article DOI: 10.1021/jm960840h BindingDB Entry DOI: 10.7270/Q28K79R6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 1 (Mus musculus) | BDBM50034912 ((S)-2-((R)-2-Acetylamino-3-phenyl-propionylamino)-...) | KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Agonist activity at mouse MC1 receptor expressed in HEK-293 cells assessed as cAMP response measured after 2 hrs incubation by cAMP Alphascreen assay | ACS Med Chem Lett 6: 568-72 (2015) Article DOI: 10.1021/acsmedchemlett.5b00053 BindingDB Entry DOI: 10.7270/Q2PZ5BJP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 5 (MC5R) (Homo sapiens (Human)) | BDBM50034912 ((S)-2-((R)-2-Acetylamino-3-phenyl-propionylamino)-...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Michigan Medical Center Curated by ChEMBL | Assay Description Displacement of [125I]NDP-MSH from Melanocortin 5 receptor at 10 uM | J Med Chem 40: 2133-9 (1997) Article DOI: 10.1021/jm960840h BindingDB Entry DOI: 10.7270/Q28K79R6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Mus musculus) | BDBM50034912 ((S)-2-((R)-2-Acetylamino-3-phenyl-propionylamino)-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 2.32E+3 | n/a | n/a | n/a | n/a |
University of Florida Curated by ChEMBL | Assay Description Functional activity at the mouse melanocortin 4 receptor | J Med Chem 44: 2247-52 (2001) BindingDB Entry DOI: 10.7270/Q2GB24S4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50034912 ((S)-2-((R)-2-Acetylamino-3-phenyl-propionylamino)-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.08E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Michigan Medical Center Curated by ChEMBL | Assay Description Displacement of [125I]NDP-MSH from Melanocortin 4 receptor at 10 uM | J Med Chem 40: 2133-9 (1997) Article DOI: 10.1021/jm960840h BindingDB Entry DOI: 10.7270/Q28K79R6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 1 (Mus musculus) | BDBM50034912 ((S)-2-((R)-2-Acetylamino-3-phenyl-propionylamino)-...) | KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 4.54E+3 | n/a | n/a | n/a | n/a |
University of Florida Curated by ChEMBL | Assay Description Functional activity at the mouse melanocortin 1 receptor | J Med Chem 44: 2247-52 (2001) BindingDB Entry DOI: 10.7270/Q2GB24S4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 5 (MC5R) (Mus musculus (Mouse)) | BDBM50034912 ((S)-2-((R)-2-Acetylamino-3-phenyl-propionylamino)-...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 1.66E+3 | n/a | n/a | n/a | n/a |
University of Florida Curated by ChEMBL | Assay Description Functional activity at the mouse melanocortin 5 receptor | J Med Chem 44: 2247-52 (2001) BindingDB Entry DOI: 10.7270/Q2GB24S4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocyte-stimulating hormone receptor (Homo sapiens (Human)) | BDBM50034912 ((S)-2-((R)-2-Acetylamino-3-phenyl-propionylamino)-...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Michigan Medical Center Curated by ChEMBL | Assay Description Displacement of [125I]NDP-MSH from Melanocortin 1 receptor at 10 uM | J Med Chem 40: 2133-9 (1997) Article DOI: 10.1021/jm960840h BindingDB Entry DOI: 10.7270/Q28K79R6 | |||||||||||
More data for this Ligand-Target Pair |