BDBM50034943 CHEMBL3338142

SMILES: CCN(Cc1cc(ccc1-c1cc(CC(O)=O)c2ccnn2c1)C(F)(F)F)C(=O)C1CC1

InChI Key: InChIKey=HQNVJESUZFWSCE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50034943   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM50034943 (CHEMBL3338142) Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)c2ccnn2c1)C(F)(F)F)C(=O)C1CC1 Show InChI InChI=1S/C23H22F3N3O3/c1-2-28(22(32)14-3-4-14)12-17-10-18(23(24,25)26)5-6-19(17)16-9-15(11-21(30)31)20-7-8-27-29(20)13-16/h5-10,13-14H,2-4,11-12H2,1H3,(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	123	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTh2 receptor (unknown origin) overexpressed in CHOK1 cell membranes assessed as inhibition of [35S]-GTPgammaS binding at 1 t...				Bioorg Med Chem Lett 24: 5118-22 (2014) Article DOI: 10.1016/j.bmcl.2014.09.005 BindingDB Entry DOI: 10.7270/Q2H70HFQ
					More data for this Ligand-Target Pair