BDBM50034949 2-Amino-6-(3,5-dichloro-phenylamino)-3H-pyrimidin-4-one::CHEMBL301283

SMILES: Nc1nc(Nc2cc(Cl)cc(Cl)c2)cc(=O)[nH]1

InChI Key: InChIKey=RRVGSKJQAFDHMO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50034949   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA helicase/primase complex protein (Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)	BDBM50034949 (2-Amino-6-(3,5-dichloro-phenylamino)-3H-pyrimidin-...) Show SMILES Nc1nc(Nc2cc(Cl)cc(Cl)c2)cc(=O)[nH]1 Show InChI InChI=1S/C10H8Cl2N4O/c11-5-1-6(12)3-7(2-5)14-8-4-9(17)16-10(13)15-8/h1-4H,(H4,13,14,15,16,17)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	770	n/a	n/a	n/a	n/a	n/a	n/a
Stanford University Medical School Curated by ChEMBL					Assay Description Inhibition against DNA-Dependent GTPase activity of HSV-1 helicase-primase in HSV-1-infected CV-1 cells				J Med Chem 38: 1820-5 (1995) BindingDB Entry DOI: 10.7270/Q29K4983
					More data for this Ligand-Target Pair