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SMILES: Cc1noc(C)c1Cc1cc(F)ccc1-n1cc(CC(O)=O)c2ccc(C)nc12

InChI Key: InChIKey=HVSDALILRLCKRH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50035038   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM50035038
PNG
(CHEMBL3338269)
Show SMILES Cc1noc(C)c1Cc1cc(F)ccc1-n1cc(CC(O)=O)c2ccc(C)nc12
Show InChI InChI=1S/C22H20FN3O3/c1-12-4-6-18-16(10-21(27)28)11-26(22(18)24-12)20-7-5-17(23)8-15(20)9-19-13(2)25-29-14(19)3/h4-8,11H,9-10H2,1-3H3,(H,27,28)
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n/an/a 2n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Antagonist activity at CRTh2 (unknown origin) stably expressed in PGD2-stimulated CHO.K1 cells preincubated for 1 hr by radio-labelled [35S]-GTPgamma...

Bioorg Med Chem Lett 24: 5127-33 (2014)


Article DOI: 10.1016/j.bmcl.2014.08.028
BindingDB Entry DOI: 10.7270/Q27P911Z
More data for this
Ligand-Target Pair