Found 4 hits for monomerid = 50035173 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50035173
(CHEMBL3343323)Show SMILES OC[C@H]1OC(NS(=O)(=O)NO)C=C[C@H]1O |r,c:11| Show InChI InChI=1S/C6H12N2O6S/c9-3-5-4(10)1-2-6(14-5)7-15(12,13)8-11/h1-2,4-11H,3H2/t4-,5-,6?/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 44 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ecole Nationale Sup£rieure de Chimie de Montpellier
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CA9 catalytic domain by stopped flow CO2 hydration assay |
Bioorg Med Chem 22: 6353-9 (2014)
Article DOI: 10.1016/j.bmc.2014.09.053 BindingDB Entry DOI: 10.7270/Q2VD713X |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50035173
(CHEMBL3343323)Show SMILES OC[C@H]1OC(NS(=O)(=O)NO)C=C[C@H]1O |r,c:11| Show InChI InChI=1S/C6H12N2O6S/c9-3-5-4(10)1-2-6(14-5)7-15(12,13)8-11/h1-2,4-11H,3H2/t4-,5-,6?/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 68 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ecole Nationale Sup£rieure de Chimie de Montpellier
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CA12 catalytic domain by stopped flow CO2 hydration assay |
Bioorg Med Chem 22: 6353-9 (2014)
Article DOI: 10.1016/j.bmc.2014.09.053 BindingDB Entry DOI: 10.7270/Q2VD713X |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50035173
(CHEMBL3343323)Show SMILES OC[C@H]1OC(NS(=O)(=O)NO)C=C[C@H]1O |r,c:11| Show InChI InChI=1S/C6H12N2O6S/c9-3-5-4(10)1-2-6(14-5)7-15(12,13)8-11/h1-2,4-11H,3H2/t4-,5-,6?/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 917 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ecole Nationale Sup£rieure de Chimie de Montpellier
Curated by ChEMBL
| Assay Description Inhibition of human full length CA1 by stopped flow CO2 hydration assay |
Bioorg Med Chem 22: 6353-9 (2014)
Article DOI: 10.1016/j.bmc.2014.09.053 BindingDB Entry DOI: 10.7270/Q2VD713X |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50035173
(CHEMBL3343323)Show SMILES OC[C@H]1OC(NS(=O)(=O)NO)C=C[C@H]1O |r,c:11| Show InChI InChI=1S/C6H12N2O6S/c9-3-5-4(10)1-2-6(14-5)7-15(12,13)8-11/h1-2,4-11H,3H2/t4-,5-,6?/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ecole Nationale Sup£rieure de Chimie de Montpellier
Curated by ChEMBL
| Assay Description Inhibition of human full length CA2 by stopped flow CO2 hydration assay |
Bioorg Med Chem 22: 6353-9 (2014)
Article DOI: 10.1016/j.bmc.2014.09.053 BindingDB Entry DOI: 10.7270/Q2VD713X |
More data for this Ligand-Target Pair | |