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SMILES: C1Cc2ccccc2C2C1C2c1ccncc1

InChI Key: InChIKey=KNIGVLQBCXKAGG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50035209   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aromatase (Homo sapiens (Human))	BDBM50035209 (4-(1a,2,3,7b-Tetrahydro-1H-cyclopropa[a]naphthalen...) Show SMILES C1Cc2ccccc2C2C1C2c1ccncc1 Show InChI InChI=1S/C16H15N/c1-2-4-13-11(3-1)5-6-14-15(16(13)14)12-7-9-17-10-8-12/h1-4,7-10,14-16H,5-6H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	185	n/a	n/a	n/a	n/a	n/a	n/a
Universität des Saarlandes Curated by ChEMBL					Assay Description Inhibition of Human placental Cytochrome P450 19A1				J Med Chem 38: 2103-11 (1995) BindingDB Entry DOI: 10.7270/Q2NV9H9S
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50035209 (4-(1a,2,3,7b-Tetrahydro-1H-cyclopropa[a]naphthalen...) Show SMILES C1Cc2ccccc2C2C1C2c1ccncc1 Show InChI InChI=1S/C16H15N/c1-2-4-13-11(3-1)5-6-14-15(16(13)14)12-7-9-17-10-8-12/h1-4,7-10,14-16H,5-6H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universität de Saarlandes Curated by ChEMBL					Assay Description In vitro inhibitory activity against Steroidgenic Cytochrome P450 17 alpha using rat testicular microsomes.				J Med Chem 39: 834-41 (1996) Article DOI: 10.1021/jm950377t BindingDB Entry DOI: 10.7270/Q29K499J
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Rattus norvegicus)	BDBM50035209 (4-(1a,2,3,7b-Tetrahydro-1H-cyclopropa[a]naphthalen...) Show SMILES C1Cc2ccccc2C2C1C2c1ccncc1 Show InChI InChI=1S/C16H15N/c1-2-4-13-11(3-1)5-6-14-15(16(13)14)12-7-9-17-10-8-12/h1-4,7-10,14-16H,5-6H2	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universität des Saarlandes Curated by ChEMBL					Assay Description In vitro inhibition of ACTH-stimulated aldosterone biosynthesis in rat adrenal slices				J Med Chem 38: 2103-11 (1995) BindingDB Entry DOI: 10.7270/Q2NV9H9S
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50035209 (4-(1a,2,3,7b-Tetrahydro-1H-cyclopropa[a]naphthalen...) Show SMILES C1Cc2ccccc2C2C1C2c1ccncc1 Show InChI InChI=1S/C16H15N/c1-2-4-13-11(3-1)5-6-14-15(16(13)14)12-7-9-17-10-8-12/h1-4,7-10,14-16H,5-6H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universität de Saarlandes Curated by ChEMBL					Assay Description Inhibitory activity against Steroidgenic Cytochrome P450 C18 using Bovine adrenal mitochondria.				J Med Chem 39: 834-41 (1996) Article DOI: 10.1021/jm950377t BindingDB Entry DOI: 10.7270/Q29K499J
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50035209 (4-(1a,2,3,7b-Tetrahydro-1H-cyclopropa[a]naphthalen...) Show SMILES C1Cc2ccccc2C2C1C2c1ccncc1 Show InChI InChI=1S/C16H15N/c1-2-4-13-11(3-1)5-6-14-15(16(13)14)12-7-9-17-10-8-12/h1-4,7-10,14-16H,5-6H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Universität de Saarlandes Curated by ChEMBL					Assay Description In vitro inhibitory activity against Cytochrome P450 19A1 using human placental microsomes.				J Med Chem 39: 834-41 (1996) Article DOI: 10.1021/jm950377t BindingDB Entry DOI: 10.7270/Q29K499J
					More data for this Ligand-Target Pair