BDBM50035306 (1-Chloro-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-dipropyl-amine::CHEMBL303021

SMILES: CCCN(CCC)C1CCc2ccc3[nH]cc(Cl)c3c2C1

InChI Key: InChIKey=AXWVKOPRBOVXMC-UHFFFAOYSA-N

Data: 6 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50035306   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50035306 ((1-Chloro-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl...) Show SMILES CCCN(CCC)C1CCc2ccc3[nH]cc(Cl)c3c2C1 Show InChI InChI=1S/C18H25ClN2/c1-3-9-21(10-4-2)14-7-5-13-6-8-17-18(15(13)11-14)16(19)12-20-17/h6,8,12,14,20H,3-5,7,9-11H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Göteborg University Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 1A receptor from CHO-K1 cells, using [3H]-8-OH-DPAT as the radioligand.				J Med Chem 38: 2202-16 (1995) BindingDB Entry DOI: 10.7270/Q24T6HD0
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50035306 ((1-Chloro-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl...) Show SMILES CCCN(CCC)C1CCc2ccc3[nH]cc(Cl)c3c2C1 Show InChI InChI=1S/C18H25ClN2/c1-3-9-21(10-4-2)14-7-5-13-6-8-17-18(15(13)11-14)16(19)12-20-17/h6,8,12,14,20H,3-5,7,9-11H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	9.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Göteborg University Curated by ChEMBL					Assay Description Binding affinity against Dopamine receptor D2 expressed in CHO-K1 cells, using [3H]-U-86,170 as the radioligand.				J Med Chem 38: 2202-16 (1995) BindingDB Entry DOI: 10.7270/Q24T6HD0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50035306 ((1-Chloro-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl...) Show SMILES CCCN(CCC)C1CCc2ccc3[nH]cc(Cl)c3c2C1 Show InChI InChI=1S/C18H25ClN2/c1-3-9-21(10-4-2)14-7-5-13-6-8-17-18(15(13)11-14)16(19)12-20-17/h6,8,12,14,20H,3-5,7,9-11H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	12.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Göteborg University Curated by ChEMBL					Assay Description Displacement of the radioligand [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor				J Med Chem 37: 3263-73 (1994) BindingDB Entry DOI: 10.7270/Q21R6PJ7
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Rattus norvegicus (Rat))	BDBM50035306 ((1-Chloro-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl...) Show SMILES CCCN(CCC)C1CCc2ccc3[nH]cc(Cl)c3c2C1 Show InChI InChI=1S/C18H25ClN2/c1-3-9-21(10-4-2)14-7-5-13-6-8-17-18(15(13)11-14)16(19)12-20-17/h6,8,12,14,20H,3-5,7,9-11H2,1-2H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Göteborg University Curated by ChEMBL					Assay Description Binding affinity against Dopamine receptor D3 expressed in CHO-K1 cells, using [3H]-spiperone as the radioligand.				J Med Chem 38: 2202-16 (1995) BindingDB Entry DOI: 10.7270/Q24T6HD0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50035306 ((1-Chloro-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl...) Show SMILES CCCN(CCC)C1CCc2ccc3[nH]cc(Cl)c3c2C1 Show InChI InChI=1S/C18H25ClN2/c1-3-9-21(10-4-2)14-7-5-13-6-8-17-18(15(13)11-14)16(19)12-20-17/h6,8,12,14,20H,3-5,7,9-11H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Göteborg University Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 1D receptor alpha expressed in CHO-K1 cells, using [3H]-5-HT as the radioligand.				J Med Chem 38: 2202-16 (1995) BindingDB Entry DOI: 10.7270/Q24T6HD0
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50035306 ((1-Chloro-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl...) Show SMILES CCCN(CCC)C1CCc2ccc3[nH]cc(Cl)c3c2C1 Show InChI InChI=1S/C18H25ClN2/c1-3-9-21(10-4-2)14-7-5-13-6-8-17-18(15(13)11-14)16(19)12-20-17/h6,8,12,14,20H,3-5,7,9-11H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	317	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Göteborg University Curated by ChEMBL					Assay Description Displacement of the radioligand [3H]-spiperone from D2 receptor				J Med Chem 37: 3263-73 (1994) BindingDB Entry DOI: 10.7270/Q21R6PJ7
					More data for this Ligand-Target Pair