BDBM50035389 CHEMBL3343368

SMILES: COc1cc2c(Oc3ccc(NC(=O)c4nnn(c4C(F)(F)F)-c4ccccc4C(F)(F)F)cc3F)ccnc2cc1OCCCN1CCCC1

InChI Key: InChIKey=XXKOUGFWCFKCQQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50035389   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50035389 (CHEMBL3343368) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4nnn(c4C(F)(F)F)-c4ccccc4C(F)(F)F)cc3F)ccnc2cc1OCCCN1CCCC1 Show InChI InChI=1S/C34H29F7N6O4/c1-49-28-18-21-24(19-29(28)50-16-6-15-46-13-4-5-14-46)42-12-11-26(21)51-27-10-9-20(17-23(27)35)43-32(48)30-31(34(39,40)41)47(45-44-30)25-8-3-2-7-22(25)33(36,37)38/h2-3,7-12,17-19H,4-6,13-16H2,1H3,(H,43,48)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 22: 6438-52 (2014) Article DOI: 10.1016/j.bmc.2014.09.037 BindingDB Entry DOI: 10.7270/Q2BG2QM2
					More data for this Ligand-Target Pair