BDBM50035411 CHEMBL3343385

SMILES: COc1cc2c(Oc3ccc(NC(=O)c4nnn(c4C(F)(F)F)-c4ccc(F)c(F)c4)cc3F)ccnc2cc1OCCCN1CCCCC1

InChI Key: InChIKey=YGRLBDZCAHOYME-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50035411   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50035411 (CHEMBL3343385) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4nnn(c4C(F)(F)F)-c4ccc(F)c(F)c4)cc3F)ccnc2cc1OCCCN1CCCCC1 Show InChI InChI=1S/C34H30F6N6O4/c1-48-29-18-22-26(19-30(29)49-15-5-14-45-12-3-2-4-13-45)41-11-10-27(22)50-28-9-6-20(16-25(28)37)42-33(47)31-32(34(38,39)40)46(44-43-31)21-7-8-23(35)24(36)17-21/h6-11,16-19H,2-5,12-15H2,1H3,(H,42,47)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 22: 6438-52 (2014) Article DOI: 10.1016/j.bmc.2014.09.037 BindingDB Entry DOI: 10.7270/Q2BG2QM2
					More data for this Ligand-Target Pair