BDBM50035419 CHEMBL3343392

SMILES: COc1cc2c(Oc3ccc(NC(=O)c4nnn(c4C(F)(F)F)-c4ccccc4C(F)(F)F)cc3F)ccnc2cc1OCCCN1CCC(C)CC1

InChI Key: InChIKey=UVKUURMGKLVPAN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50035419   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50035419 (CHEMBL3343392) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4nnn(c4C(F)(F)F)-c4ccccc4C(F)(F)F)cc3F)ccnc2cc1OCCCN1CCC(C)CC1 Show InChI InChI=1S/C36H33F7N6O4/c1-21-11-15-48(16-12-21)14-5-17-52-31-20-26-23(19-30(31)51-2)28(10-13-44-26)53-29-9-8-22(18-25(29)37)45-34(50)32-33(36(41,42)43)49(47-46-32)27-7-4-3-6-24(27)35(38,39)40/h3-4,6-10,13,18-21H,5,11-12,14-17H2,1-2H3,(H,45,50)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 22: 6438-52 (2014) Article DOI: 10.1016/j.bmc.2014.09.037 BindingDB Entry DOI: 10.7270/Q2BG2QM2
					More data for this Ligand-Target Pair