BDBM50035546 5-(4-tert-Butyl-phenyl)-9-chloro-2,3-dihydro-imidazo[2,1-a]isoquinoline::CHEMBL78137

SMILES: CC(C)(C)c1ccc(cc1)C1=Cc2ccc(Cl)cc2C2=NCCN12

InChI Key: InChIKey=RIUGQGXKSXIENE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50035546   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet activating factor receptor (Homo sapiens (Human))	BDBM50035546 (5-(4-tert-Butyl-phenyl)-9-chloro-2,3-dihydro-imida...) Show SMILES CC(C)(C)c1ccc(cc1)C1=Cc2ccc(Cl)cc2C2=NCCN12 |t:11,21| Show InChI InChI=1S/C21H21ClN2/c1-21(2,3)16-7-4-14(5-8-16)19-12-15-6-9-17(22)13-18(15)20-23-10-11-24(19)20/h4-9,12-13H,10-11H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.04E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sandoz Research Institute Curated by ChEMBL					Assay Description Inhibition of [3H]-PAF binding to human platelet activating factor receptor				J Med Chem 38: 234-40 (1995) BindingDB Entry DOI: 10.7270/Q27M06Z1
					More data for this Ligand-Target Pair