BDBM50035570 5-(4-Thiomorpholin-4-ylmethyl-phenyl)-2,3-dihydro-imidazo[2,1-a]isoquinoline::CHEMBL420208

SMILES: C(N1CCSCC1)c1ccc(cc1)C1=Cc2ccccc2C2=NCCN12

InChI Key: InChIKey=OIDKHURQGVYQBG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50035570   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet activating factor receptor (Homo sapiens (Human))	BDBM50035570 (5-(4-Thiomorpholin-4-ylmethyl-phenyl)-2,3-dihydro-...) Show SMILES C(N1CCSCC1)c1ccc(cc1)C1=Cc2ccccc2C2=NCCN12 |t:15,24| Show InChI InChI=1S/C22H23N3S/c1-2-4-20-19(3-1)15-21(25-10-9-23-22(20)25)18-7-5-17(6-8-18)16-24-11-13-26-14-12-24/h1-8,15H,9-14,16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sandoz Research Institute Curated by ChEMBL					Assay Description Inhibition of [3H]-PAF binding to human platelet activating factor receptor				J Med Chem 38: 234-40 (1995) BindingDB Entry DOI: 10.7270/Q27M06Z1
					More data for this Ligand-Target Pair